Medicines of the central action, such as Neurontin are used for the treatment of neuralgia and convulsive attacks. These drugs should render selective effect on the mechanisms of pain development and convulsive attacks, without affecting other neural mechanisms. Neurontin meets all these requirements.
The active substance of Neurontin is Gabapentin. This drug is similar to gamma-aminobutyric acid (GABA) in its structure, but it does not have affinity with GABA receptors.
Analgesic and anticonvulsant effect of Gabapentin is associated with blocking of the flow of calcium ions, responsible for the neuropathic pain appearance. In addition, Gabapentin indirectly increases the synthesis of GABA.
Pharmaceutical form of Neurontin
- Neurontin capsules 100, 300, 400mg
- Neurontin tablets 600, 800mg
- Indications to Neurontin use
Neurontin is intended for adults to treat neuropathic pain, as well as monotherapy or as an additional drug in the treatment of partial seizures in adults and children.
Neurontin dosage
For adults and children older than 12 years, the treatment is started with 900 mg of Neurontin once a day, divided into 3 doses. Later, it is possibly the increasing of dose up to 3.6 g of Neurontin once a day (the maximum daily dose).
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